Hi,
Has anybody ever tried to play the game with all 6 heroic sets combined?
What do you need to do to keep the quests managable with that many rooms?
Otherwise, what's the maximum number of sets you should play with? 2-deck wilderness + 2-deck dungeon? (110 + 110)
wow, all sets in a single combined game. That's crazy! Tell me how it goes, and please take pictures. 
Generally 2-3 sets is what we've used in playtests. And 4 only when we've played through all levels of play: heroic-epic-legendary.
Thanks for the reply,
What we ended up doing was to use all the treasure/boons/monsters/banes from every set, seperated into 2 decks.
For the quests/locations cards, we only used from 2 sets, 1 wilderness and 1 dungeon.
It went fairly well, except some of the cards who are region specific were pretty much useless if the appropriate location cards are not included.