Mythic Europe setting for another game system?

Has anyone ever used the Mythic Europe setting while playing a game other than Ars Magica? What stayed the same in the setting? What was altered? What game were you playing? How did it go?

'Cause I really think I've found a way to use Mythic Europe with D&D Fifth Edition.

It's a different flavor of Mythic Europe, but in a second game we're playing with D&D 3.5 though, it's a Call of Cthulu game.