When one addresses something like this, especially as a Story Guide (which is the level for a lot of these questions, since many players just don't worry about things at this level), we have to make sure the interpretation applies to all situations...
So, if a mage casts PeAn to destroy leather armour, say on a soldier in the road, then any soldier who wanders into that "Animal hole" has their leather bits destroyed? if the mage casts PeCo "Dust to Dust" with a duration, at a zombie in a doorway, then any zombie who wanders into that "Corpus hole" is then also destroyed? And does that work for other Techniques, and if not why not? Or, what, if anything, makes a "hole" a valid target, but not a road or a doorway?
Yes, it does appear problematic, or at least at first pass - let's see if we can't figure it out. And we do that by looking to the rules...
Many PeFo effects do not need to work this way, and only need momentary - you see what you want gone, it goes away, end of discussion. But what if you did have those same effects with a continuing duration, what would happen?
Canon Mentem spells clearly do work this way, as the first line of the PeMe Guidelines state: "Emotions naturally reappear in a person, so so spells that destroy them must have a continuing Duration to ensure that they do not come back..."
Such Targets are individual minds, not physical locations (a pillow, a hallway), so they don't lay in wait for the next mind as some of the above examples, but they do lay in wait for the next appropriate thought/emotion to fill that mind.
PeIm also emphasizes the use of continuing Durations, and even addresses (in its own unique sense) targets that change during that duration, by adding a magnitude for images that change, etc.
There are additional examples for PeAq(Au) (Odious Drought), PeIm, and in the PeVi guidelines. So one clearly can use Perdo to "target" things not yet sensed.
So how do we explain this within Hermetic Theory?
(LOL - and I'm not going to - or not right now - phone call from a client, gotta run, so I'm gonna post this and bail - sorry!)