I've looked and looked, but couldn't seem to find anything in the 5th ed core book. I seem to remember some things from 4th ed that don't quite hold true anymore, I think.
The V&Fs Giant Blood, Dwarf, Large, Small frame all affect Size, and Size affects the range og damage needed for the different Wound Levels, I'm down with that. Also, Giant Blood and Dwarf actually give +/-1 STR and STM, thus affecting Soak, Fatigue rolls and Dam.
But does Size subtract from Defence anymore? From Initiative?, Add (further) to Dam?
This leads to funny results, where a MuCo spell can enlarge you, without changing your str or sta. Thus, you could become size 6+ without any special advantage save an increased wound range...